Ontology highlight
ABSTRACT:
SUBMITTER: Low SK
PROVIDER: S-EPMC6874604 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Low Siew-Kee SK Chin Yoon Ming YM Ito Hidemi H Matsuo Keitaro K Tanikawa Chizu C Matsuda Koichi K Saito Hiroko H Sakurai-Yageta Mika M Nakaya Naoki N Shimizu Atsushi A Nishizuka Satoshi S SS Yamaji Taiki T Sawada Norie N Iwasaki Motoki M Tsugane Shoichiro S Takezaki Toshiro T Suzuki Sadao S Naito Mariko M Wakai Kenji K Kamatani Yoichiro Y Momozawa Yukihide Y Murakami Yoshinori Y Inazawa Johji J Nakamura Yusuke Y Kubo Michiaki M Katagiri Toyomasa T Miki Yoshio Y
Scientific reports 20191122 1
Genome-wide association studies (GWAS) have successfully identified about 70 genomic loci associated with breast cancer. Owing to the complexity of linkage disequilibrium and environmental exposures in different populations, it is essential to perform regional GWAS for better risk prediction. This study aimed to investigate the genetic architecture and to assess common genetic risk model of breast cancer with 6,669 breast cancer patients and 21,930 female controls in the Japanese population. Thi ...[more]