Ontology highlight
ABSTRACT:
SUBMITTER: Alkemade A
PROVIDER: S-EPMC6875153 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Alkemade Anneke A de Hollander Gilles G Miletic Steven S Keuken Max C MC Balesar Rawien R de Boer Onno O Swaab Dick F DF Forstmann Birte U BU
Brain structure & function 20190928 9
The subthalamic nucleus (STN) is successfully used as a surgical target for deep brain stimulation in the treatment of movement disorders. Interestingly, the internal structure of the STN is still incompletely understood. The objective of the present study was to investigate three-dimensional (3D) immunoreactivity patterns for 12 individual protein markers for GABA-ergic, serotonergic, dopaminergic as well as glutamatergic signaling. We analyzed the immunoreactivity using optical densities and c ...[more]