Ontology highlight
ABSTRACT:
SUBMITTER: Ayuk F
PROVIDER: S-EPMC6876613 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Ayuk Francis F Bornhäuser Martin M Stelljes Matthias M Zabelina Tatjana T Wagner Eva-Maria EM Schmid Christoph C Christopeit Maximilian M Guellstorf Martina M Kröger Nicolaus N Bethge Wolfgang W
Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie 20190829 5
There is no established standard for selection of mismatched unrelated donors. Indirect recognition of HLA mismatches can be predicted using the model of "Predicted Indirectly ReCognizable HLA Epitopes" (PIRCHE). We performed a multicenter retrospective study evaluating the impact PIRCHE on outcome after allogeneic stem cell transplantation (allo-HSCT) from single mismatched (HLA 9/10 matched) unrelated donors. The study cohort included 424 adult recipients of HLA 9/10 matched unrelated donor tr ...[more]