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Sequenceserver: A Modern Graphical User Interface for Custom BLAST Databases.

ABSTRACT: Comparing newly obtained and previously known nucleotide and amino-acid sequences underpins modern biological research. BLAST is a well-established tool for such comparisons but is challenging to use on new data sets. We combined a user-centric design philosophy with sustainable software development approaches to create Sequenceserver, a tool for running BLAST and visually inspecting BLAST results for biological interpretation. Sequenceserver uses simple algorithms to prevent potential analysis errors and provides flexible text-based and visual outputs to support researcher productivity. Our software can be rapidly installed for use by individuals or on shared servers.

SUBMITTER: Priyam A

PROVIDER: S-EPMC6878946 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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Sequenceserver: A Modern Graphical User Interface for Custom BLAST Databases.

Priyam Anurag A Woodcroft Ben J BJ Rai Vivek V Moghul Ismail I Munagala Alekhya A Ter Filip F Chowdhary Hiten H Pieniak Iwo I Maynard Lawrence J LJ Gibbins Mark Anthony MA Moon HongKee H Davis-Richardson Austin A Uludag Mahmut M Watson-Haigh Nathan S NS Challis Richard R Nakamura Hiroyuki H Favreau Emeline E Gómez Esteban A EA Pluskal Tomás T Leonard Guy G Rumpf Wolfgang W Wurm Yannick Y

Molecular biology and evolution 20191201 12

Comparing newly obtained and previously known nucleotide and amino-acid sequences underpins modern biological research. BLAST is a well-established tool for such comparisons but is challenging to use on new data sets. We combined a user-centric design philosophy with sustainable software development approaches to create Sequenceserver, a tool for running BLAST and visually inspecting BLAST results for biological interpretation. Sequenceserver uses simple algorithms to prevent potential analysis ...[more]

PMID: 31411700

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