Ontology highlight
ABSTRACT:
SUBMITTER: Saini H
PROVIDER: S-EPMC6879206 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Saini Harleen H Bicknell Alicia A AA Eddy Sean R SR Moore Melissa J MJ
eLife 20191107
The polarized structure of axons and dendrites in neuronal cells depends in part on RNA localization. Previous studies have looked at which polyadenylated RNAs are enriched in neuronal projections or at synapses, but less is known about the distribution of non-adenylated RNAs. By physically dissecting projections from cell bodies of primary rat hippocampal neurons and sequencing total RNA, we found an unexpected set of free circular introns with a non-canonical branchpoint enriched in neuronal p ...[more]