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[Research Progress of Tumor-Associated Neutrophils and Lung Cancer].

ABSTRACT: Lung cancer is a global disease with high morbidity and mortality, which seriously affects human health. The long-term existence of chronic pulmonary inflammation is closely related to the occurrence and development of lung cancer, neutrophils are not only involved in acute and chronic inflammation, but also in the composition of tumor microenvironment (TME), which is closely related to the occurrence and development of tumors. Recent studies have found that tumor-associated neutrophils (TANs) play an important role in the occurrence and development of lung cancer. This article reviews the role, mechanism and clinical significance of tumor-related neutrophils in lung cancer.

SUBMITTER: Zhou J

PROVIDER: S-EPMC6885416 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature

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[Research Progress of Tumor-Associated Neutrophils and Lung Cancer].

Zhou Jinhua J Jiang Shulong S Wang Wei W Liu Ruijuan R

Zhongguo fei ai za zhi = Chinese journal of lung cancer 20191101 11

Lung cancer is a global disease with high morbidity and mortality, which seriously affects human health. The long-term existence of chronic pulmonary inflammation is closely related to the occurrence and development of lung cancer, neutrophils are not only involved in acute and chronic inflammation, but also in the composition of tumor microenvironment (TME), which is closely related to the occurrence and development of tumors. Recent studies have found that tumor-associated neutrophils (TANs) p ...[more]

PMID: 31771743

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