Ontology highlight
ABSTRACT:
SUBMITTER: Hu WE
PROVIDER: S-EPMC6886862 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Hu Wan-Er WE Zhang Xin X Guo Qiu-Fang QF Yang Jing-Wei JW Yang Yuan Y Wei Shi-Cheng SC Su Xiao-Dong XD
PloS one 20191202 12
The HeLa cells are the earliest and mostly used laboratory human cells for biomedical particularly cancer research. They were derived from a patient's cervical cancerous tissue, and are known for their heterogeneous cellular origin and variable genomic landscapes. Single-cell sequencing techniques with faithful linear and uniformly amplified genomes (DNA) and transcriptomes (RNA) may facilitate the study of cellular differences at the individual cell level. In this work, we have performed single ...[more]