Ontology highlight
ABSTRACT:
SUBMITTER: Garcia-Miranda P
PROVIDER: S-EPMC6887710 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
García-Miranda Pablo P Morón-Civanto Francisco J FJ Martínez-Olivo Maria Del Mar MDM Suárez-Luna Nela N Ramírez-Lorca Reposo R Lebrato-Hernández Lucía L Lamas-Pérez Raquel R Navarro Guillermo G Abril-Jaramillo Javier J García-Sánchez Maria Isabel MI Casado-Chocán José Luis JL Uclés-Sánchez Antonio José AJ Romera Mercedes M Echevarría Miriam M Díaz-Sánchez María M
International journal of molecular sciences 20191119 22
The detection of IgG aquaporin-4 antibodies in the serum of patients with Neuromyelitis optica (NMO) has dramatically improved the diagnosis of this disease and its distinction from multiple sclerosis. Recently, a group of patients have been described who have an NMO spectrum disorder (NMOsd) and who are seronegative for AQP4 antibodies but positive for IgG aquaporin-1 (AQP1) or myelin oligodendrocyte glycoprotein (MOG) antibodies. The purpose of this study was to determine whether AQP1 and MOG ...[more]