Ontology highlight
ABSTRACT:
SUBMITTER: Shigemura M
PROVIDER: S-EPMC6890671 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Shigemura Masahiko M Lecuona Emilia E Angulo Martín M Dada Laura A LA Edwards Melanie B MB Welch Lynn C LC Casalino-Matsuda S Marina SM Sporn Peter H S PHS Vadász István I Helenius Iiro Taneli IT Nader Gustavo A GA Gruenbaum Yosef Y Sharabi Kfir K Cummins Eoin E Taylor Cormac C Bharat Ankit A Gottardi Cara J CJ Beitel Greg J GJ Kaminski Naftali N Budinger G R Scott GRS Berdnikovs Sergejs S Sznajder Jacob I JI
Scientific reports 20191203 1
Carbon dioxide (CO<sub>2</sub>) is sensed by cells and can trigger signals to modify gene expression in different tissues leading to changes in organismal functions. Despite accumulating evidence that several pathways in various organisms are responsive to CO<sub>2</sub> elevation (hypercapnia), it has yet to be elucidated how hypercapnia activates genes and signaling pathways, or whether they interact, are integrated, or are conserved across species. Here, we performed a large-scale transcripto ...[more]