Ontology highlight
ABSTRACT:
SUBMITTER: Scott CJ
PROVIDER: S-EPMC6891000 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Scott Catherine J CJ Jiao Jieqing J Melbourne Andrew A Burgos Ninon N Cash David M DM De Vita Enrico E Markiewicz Pawel J PJ O'Connor Antoinette A Thomas David L DL Weston Philip Sj PS Schott Jonathan M JM Hutton Brian F BF Ourselin Sébastien S
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20180905 12
Pharmacokinetic modelling on dynamic positron emission tomography (PET) data is a quantitative technique. However, the long acquisition time is prohibitive for routine clinical use. Instead, the semi-quantitative standardised uptake value ratio (SUVR) from a shorter static acquisition is used, despite its sensitivity to blood flow confounding longitudinal analysis. A method has been proposed to reduce the dynamic acquisition time for quantification by incorporating cerebral blood flow (CBF) info ...[more]