Ontology highlight
ABSTRACT:
SUBMITTER: Basabe-Burgos O
PROVIDER: S-EPMC6892477 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Basabe-Burgos Oihana O Ahlström Jakub Zebialowicz JZ Mikolka Pavol P Landreh Michael M Johansson Jan J Curstedt Tore T Rising Anna A
PloS one 20191204 12
Pulmonary surfactant preparations extracted from natural sources have been used to treat millions of newborn babies with respiratory distress syndrome (RDS) and can possibly also be used to treat other lung diseases. Due to costly production and limited supply of animal-derived surfactants, synthetic alternatives are attractive. The water insolubility and aggregation-prone nature of the proteins present in animal-derived surfactant preparations have complicated development of artificial surfacta ...[more]