Ontology highlight
ABSTRACT:
SUBMITTER: Hirschmugl B
PROVIDER: S-EPMC6893815 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Hirschmugl Birgit B Brandl Waltraud W Csapo Bence B van Poppel Mireille M Köfeler Harald H Desoye Gernot G Wadsack Christian C Jantscher-Krenn Evelyn E
Nutrients 20191104 11
Human milk oligosaccharides (HMOs) are present in maternal serum in early gestation, raising the question of whether HMOs can cross the placental barrier and reach fetal circulation. Here, we aimed to detect HMOs in cord blood, and assess HMO composition and concentration in relation to maternal HMOs. In an ex-vivo placental perfusion model, we asked whether HMOs can pass over the placenta. Using HPLC, we measured HMOs in maternal serum and matching venous cord blood samples collected at deliver ...[more]