Ontology highlight
ABSTRACT:
SUBMITTER: Wu X
PROVIDER: S-EPMC6894291 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Clinical epigenetics 20191204 1
<h4>Background</h4>Smoking leads to the aging of organs. However, no studies have been conducted to quantify the effect of smoking on the aging of respiratory organs and the aging-reversing ability of smoking cessation.<h4>Results</h4>We collected genome-wide methylation datasets of buccal cells, airway cells, esophagus tissue, and lung tissue from non-smokers, smokers, and ex-smokers. We used the "epigenetic clock" method to quantify the epigenetic age acceleration in the four organs. The stati ...[more]