Ontology highlight
ABSTRACT:
SUBMITTER: Heinemann F
PROVIDER: S-EPMC6895116 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Heinemann Fabian F Birk Gerald G Stierstorfer Birgit B
Scientific reports 20191205 1
Non-alcoholic fatty liver disease (NAFLD) and the progressive form of non-alcoholic steatohepatitis (NASH) are diseases of major importance with a high unmet medical need. Efficacy studies on novel compounds to treat NAFLD/NASH using disease models are frequently evaluated using established histological feature scores on ballooning, inflammation, steatosis and fibrosis. These features are assessed by a trained pathologist using microscopy and assigned discrete scores. We demonstrate how to autom ...[more]