Perspectives in TSPO PET Imaging for Neurologic Diseases.
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ABSTRACT:
SUBMITTER: Song YS
PROVIDER: S-EPMC6898699 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Publications
Perspectives in TSPO PET Imaging for Neurologic Diseases.
Nuclear medicine and molecular imaging 20191116 6
The translocator protein (18 kDa) (TSPO) is a mitochondrial transmembrane protein, which has brought attention as a neuroinflammatory biomarker. Positron emission tomography (PET) imaging studies have been done for several decades, since neuroinflammation has been implicated as an important pathophysiology of several common neurologic disorders. However, despite numerous previous studies with positive findings, its clinical significance is not yet clear. Various attempts to overcome the limitati ...[more]
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