Ontology highlight
ABSTRACT:
SUBMITTER: Kamburova EG
PROVIDER: S-EPMC6899679 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Kamburova Elena G EG Gruijters Maartje L ML Kardol-Hoefnagel Tineke T Wisse Bram W BW Joosten Irma I Allebes Wil A WA van der Meer Arnold A Hilbrands Luuk B LB Baas Marije C MC Spierings Eric E Hack Cornelis E CE van Reekum Franka E FE van Zuilen Arjan D AD Verhaar Marianne C MC Bots Michiel L ML Drop Adriaan C A D ACAD Plaisier Loes L Melchers Rowena C A RCA Seelen Marc A J MAJ Sanders Jan Stephan JS Hepkema Bouke G BG Lambeck Annechien J A AJA Bungener Laura B LB Roozendaal Caroline C Tilanus Marcel G J MGJ Voorter Christina E CE Wieten Lotte L van Duijnhoven Elly M EM Gelens Mariëlle A C J MACJ Christiaans Maarten H L MHL van Ittersum Frans J FJ Nurmohamed Shaikh A SA Lardy Neubury M NM Swelsen Wendy W van der Pant Karlijn A M I KAMI van der Weerd Neelke C NC Ten Berge Ineke J M IJM Hoitsma Andries A van der Boog Paul J M PJM de Fijter Johan W JW Betjes Michiel G H MGH Heidt Sebastiaan S Roelen Dave L DL Claas Frans H FH Bemelman Frederike J FJ Otten Henny G HG
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20190703 12
The clinical significance of non-HLA antibodies on renal allograft survival is a matter of debate, due to differences in reported results and lack of large-scale studies incorporating analysis of multiple non-HLA antibodies simultaneously. We developed a multiplex non-HLA antibody assay against 14 proteins highly expressed in the kidney. In this study, the presence of pretransplant non-HLA antibodies was correlated to renal allograft survival in a nationwide cohort of 4770 recipients transplante ...[more]