Ontology highlight
ABSTRACT:
SUBMITTER: Mecozzi F
PROVIDER: S-EPMC6899713 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
European journal of organic chemistry 20191031 42
A one-pot multi-step method for the oxidative cleavage of alkenes to aldehydes/ketones under ambient conditions is described as an alternative to ozonolysis. The first step is a highly efficient manganese catalyzed epoxidation/<i>cis</i>-dihydroxylation of alkenes. This step is followed by an Fe(III) assisted ring opening of the epoxide (where necessary) to a 1,2-diol. Carbon-carbon bond cleavage is achieved by treatment of the diol with sodium periodate. The conditions used in each step are not ...[more]