Ontology highlight
ABSTRACT:
SUBMITTER: Huang Z
PROVIDER: S-EPMC6901542 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Huang Zixian Z Zhang Yin Y Li Haigang H Zhou Yufeng Y Zhang Qianyu Q Chen Rui R Jin Tingting T Hu Kaishun K Li Shihao S Wang Yan Y Chen Weiliang W Huang Zhiquan Z
Cell death & disease 20191209 12
Chemoresistance is a major cause of cancer progression and the mortality of cancer patients. Developing a safe strategy for enhancing chemosensitivity is a challenge for biomedical science. Recent studies have suggested that vitamin D supplementation may decrease the risk of many cancers. However, the role of vitamin D in chemotherapy remains unknown. We found that vitamin D sensitised oral cancer cells to cisplatin and partially reversed cisplatin resistance. Using RNA-seq, we discovered that l ...[more]