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Association of smoking and physical inactivity with MRI derived changes in cardiac function and structure in cardiovascular healthy subjects.


ABSTRACT: We aimed to investigate the association of smoking and physical exercise on ventricular function and structure, determined by cardiac magnetic resonance imaging (CMR), in subjects without known cardiovascular diseases. A total of 381 participants (median age 57 years) of the Cooperative Health Research in the Region of Augsburg (KORA) FF4 cohort underwent CMR. The participants' smoking and sporting habits were measured by a questionnaire. Physical inactivity was associated with a reduction of left ventricular ejection fraction (LV-EF), stroke volume, early diastolic peak filling rate and peak ejection rate of the left ventricle as well as right ventricular stroke volume. LV-EF was reduced in subjects with almost no physical activity compared to subjects with regular physical activity (68.4%, 95%CI 66.8-70.1% vs. 70.8%, 95%CI 69.2-72.3%, p?

SUBMITTER: Schafnitzel A 

PROVIDER: S-EPMC6901589 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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Association of smoking and physical inactivity with MRI derived changes in cardiac function and structure in cardiovascular healthy subjects.

Schafnitzel Anina A   Lorbeer Roberto R   Bayerl Christian C   Patscheider Hannah H   Auweter Sigrid D SD   Meisinger Christa C   Heier Margit M   Ertl-Wagner Birgit B   Reiser Maximilian M   Peters Annette A   Bamberg Fabian F   Hetterich Holger H  

Scientific reports 20191209 1


We aimed to investigate the association of smoking and physical exercise on ventricular function and structure, determined by cardiac magnetic resonance imaging (CMR), in subjects without known cardiovascular diseases. A total of 381 participants (median age 57 years) of the Cooperative Health Research in the Region of Augsburg (KORA) FF4 cohort underwent CMR. The participants' smoking and sporting habits were measured by a questionnaire. Physical inactivity was associated with a reduction of le  ...[more]

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