Evaluation of Patch Test Findings in Patients With Anogenital Dermatitis.

ABSTRACT: Importance:Contact dermatitis in the anogenital area is associated with sleep disturbance and dyspareunia and can profoundly affect quality of life. The literature on anogenital contact dermatitis and culprit allergens is limited. The last large-scale study on common, relevant allergens in patients with anogenital dermatitis was published in 2008. Objectives:To characterize patients with anogenital dermatitis referred for patch testing by the North American Contact Dermatitis Group, to identify common allergens, and to explore sex-associated differences between anogenital dermatitis and allergens. Design, Setting, and Participants:A retrospective, cross-sectional analysis was conducted of the North American Contact Dermatitis Group database among 28?481 patients who underwent patch testing from January 1, 2005, to December 31, 2016, at outpatient referral clinics in the United States and Canada. Exposure:Patch testing for allergens. Main Outcomes and Measures:Currently relevant allergic patch test reactions in patients with anogenital dermatitis. Results:Of 28?481 patients tested during the study period, 832 patients (336 men and 496 women; mean [SD] age, 50.1 [26.5] years) had anogenital involvement and 449 patients (177 men and 272 women; mean [SD] age, 49.6 [17.4] years) had anogenital dermatitis only. Compared with those without anogenital involvement, there were significantly more male patients in the group with anogenital dermatitis (177 [39.4%] vs 8857 of 27 649 [32.0%]; relative risk, 1.37; 95% CI, 1.14-1.66; P?

SUBMITTER: Warshaw EM 

PROVIDER: S-EPMC6902099 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature