Ontology highlight
ABSTRACT:
SUBMITTER: Jia WL
PROVIDER: S-EPMC6902280 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Organic letters 20191111 23
Herein, we report a highly selective C-H olefination of directing-group-free indolines (C5) and tetrahydroquinolines (C6) by Pd/S,O-ligand catalysis. In the presence of the S,O-ligand, a wide range of challenging indolines, tetrahydroquinolines, and olefins was efficiently olefinated under mild reaction conditions. The synthetic potential of this methodology was demonstrated by the efficient olefination of several indoline-based natural products. ...[more]