Ontology highlight
ABSTRACT:
SUBMITTER: Cennamo N
PROVIDER: S-EPMC6904456 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Cennamo Nunzio N Pasquardini Laura L Arcadio Francesco F Vanzetti Lia E LE Bossi Alessandra Maria AM Zeni Luigi L
Scientific reports 20191210 1
The development of optical biosensors for the rapid and costless determination of clinical biomarkers is of paramount importance in medicine. Here we report a fast and low-cost biosensor based on a plasmonic D-shaped plastic optical fibre (POF) sensor derivatized with an aptamer specific for the recognition of thrombin, the target marker of blood homeostasis and coagulation cascade. In particular, we designed a functional interface based on a Self Assembled Monolayer (SAM) composed of short Poly ...[more]