Ontology highlight
ABSTRACT:
SUBMITTER: Chu CC
PROVIDER: S-EPMC6905585 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Chu Chia-Chieh CC Liu Bei B Plangger Raphael R Kreutz Christoph C Al-Hashimi Hashim M HM
PloS one 20191211 12
N6-methyladenosine (m6A) is a ubiquitous RNA post-transcriptional modification found in coding as well as non-coding RNAs. m6A has also been found in viral RNAs where it is proposed to modulate host-pathogen interactions. Two m6A sites have been reported in the HIV-1 Rev response element (RRE) stem IIB, one of which was shown to enhance binding to the viral protein Rev and viral RNA export. However, because these m6A sites have not been observed in other studies mapping m6A in HIV-1 RNA, their s ...[more]