Ontology highlight
ABSTRACT:
SUBMITTER: Lucchetti BFC
PROVIDER: S-EPMC6906468 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Lucchetti Bruno Fernando Cruz BFC Boaretto Natalia N Lopes Fernanda Novi Cortegoso FNC Malvezi Aparecida Donizette AD Lovo-Martins Maria Isabel MI Tatakihara Vera Lúcia Hideko VLH Fattori Victor V Pereira Rito Santo RS Verri Waldiceu Aparecido WA de Almeida Araujo Eduardo Jose EJ Pinge-Filho Phileno P Martins-Pinge Marli Cardoso MC
Scientific reports 20191211 1
We evaluated the influence of metabolic syndrome (MS) on acute Trypanosoma cruzi infection. Obese Swiss mice, 70 days of age, were subjected to intraperitoneal infection with 5 × 10<sup>2</sup> trypomastigotes of the Y strain. Cardiovascular, oxidative, inflammatory, and metabolic parameters were evaluated in infected and non-infected mice. We observed higher parasitaemia in the infected obese group (IOG) than in the infected control group (ICG) 13 and 15 days post-infection. All IOG animals die ...[more]