Dataset Information

Dietary glycaemic index and cognitive function: prospective associations in adults of the 1946 British birth cohort.

ABSTRACT:

Objective

Evidence suggests that the rate of glucose release following consumption of carbohydrate-containing foods, defined as the glycaemic index (GI), is inversely associated with cognitive function. To date, most of the evidence stems from either single-meal studies or highly heterogeneous cohort studies. We aimed to study the prospective associations of diet GI at age 53 years with outcomes of verbal memory and letter search tests at age 69 years and rate of decline between 53 and 69 years.

Design

Longitudinal population-based birth cohort study.

Setting

MRC National Survey for Health and Development.

Participants

Cohort members (n 1252).

Results

Using multivariable linear and logistic regression, adjusted for potential confounders, associations of higher-GI diet with lower verbal memory, lower letter search speed and lower number of hits in a letter search test were attenuated after adjustments for cognitive ability at age 15 years, educational attainment, further training and occupational social class. No association was observed between diet GI at 53 years and letter search accuracy or speed-accuracy trade-off at 69 years, or between diet GI at 53 years and rate of decline between 53 and 69 years in any cognitive measure.

Conclusions

Diet GI does not appear to predict cognitive function or decline, which was mainly explained by childhood cognitive ability, education and occupational social class. Our findings confirm the need for further research on the association between diet and cognition from a life-course perspective.

SUBMITTER: Philippou E

PROVIDER: S-EPMC6906611 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Dietary glycaemic index and cognitive function: prospective associations in adults of the 1946 British birth cohort.

Philippou Elena E Pot Gerda K GK Heraclides Alexandros A Richards Marcus M Bendayan Rebecca R

Public health nutrition 20181226 8

<h4>Objective</h4>Evidence suggests that the rate of glucose release following consumption of carbohydrate-containing foods, defined as the glycaemic index (GI), is inversely associated with cognitive function. To date, most of the evidence stems from either single-meal studies or highly heterogeneous cohort studies. We aimed to study the prospective associations of diet GI at age 53 years with outcomes of verbal memory and letter search tests at age 69 years and rate of decline between 53 and 6 ...[more]

PMID: 30585572

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Dataset Information

Dietary glycaemic index and cognitive function: prospective associations in adults of the 1946 British birth cohort.

Objective

Design

Setting

Participants

Results

Conclusions

Publications

Dietary glycaemic index and cognitive function: prospective associations in adults of the 1946 British birth cohort.

Similar Datasets

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