Ontology highlight
ABSTRACT:
SUBMITTER: Liu W
PROVIDER: S-EPMC6907247 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Respiratory research 20191211 1
<h4>Background</h4>Fibroblasts regulate tissue homeostasis and the balance between tissue repair and fibrosis. CCAAT/enhancer-binding protein alpha (CEBPA) is a key transcription factor that regulates adipogenesis. CEBPA has been shown to be essential for lung maturation, and deficiency of CEBPA expression leads to abnormal lung architecture. However, its specific role in lung fibroblast regulation and fibrosis has not yet been elucidated.<h4>Methods</h4>Lung fibroblast CEBPA expression, pro-fib ...[more]