Ontology highlight
ABSTRACT:
SUBMITTER: Dondossola D
PROVIDER: S-EPMC6912657 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Dondossola Daniele D Santini Alessandro A Lonati Caterina C Zanella Alberto A Merighi Riccardo R Vivona Luigi L Battistin Michele M Galli Alessandro A Biancolilli Osvaldo O Maggioni Marco M Villa Stefania S Gatti Stefano S
Journal of clinical medicine 20191108 11
Ex-situ machine perfusion (MP) has been increasingly used to enhance liver quality in different settings. Small animal models can help to implement this procedure. As most normothermic MP (NMP) models employ sub-physiological levels of oxygen delivery (DO<sub>2</sub>), the aim of this study was to investigate the effectiveness and safety of different DO<sub>2</sub>, using human red blood cells (RBCs) as oxygen carriers on metabolic recovery in a rat model of NMP. Four experimental groups (n = 5 ...[more]