Ontology highlight
ABSTRACT:
SUBMITTER: Veling MW
PROVIDER: S-EPMC6913890 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Veling Macy W MW Li Ye Y Veling Mike T MT Litts Christopher C Michki Nigel N Liu Hao H Ye Bing B Cai Dawen D
Cell reports 20191201 10
Elucidating cell lineages provides crucial understanding of development. Recently developed sequencing-based techniques enhance the scale of lineage tracing but eliminate the spatial information offered by conventional approaches. Multi-spectral labeling techniques, such as Brainbow, have the potential to identify lineage-related cells in situ. Here, we report nuclear Bitbow (nBitbow), a "digital" version of Brainbow that greatly expands the color diversity for scoring cells, and a suite of stat ...[more]