Ontology highlight
ABSTRACT:
SUBMITTER: Xiong F
PROVIDER: S-EPMC4444339 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Xiong Fengzhu F Obholzer Nikolaus D ND Noche Ramil R RR Megason Sean G SG
PloS one 20150526 5
We introduce a multicolor labeling strategy (Multibow) for cell tracing experiments in developmental and regenerative processes. Building on Brainbow-based approaches that produce colors by differential expression levels of different fluorescent proteins, Multibow adds a layer of label diversity by introducing a binary code in which reporters are initially OFF and then probabilistically ON or OFF following Cre recombination. We have developed a library of constructs that contains seven different ...[more]