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Visible-Light-Driven Intermolecular Reductive Ene-Yne Coupling by Iridium/Cobalt Dual Catalysis for C(sp³ )-C(sp² ) Bond Formation.

ABSTRACT: A new methodology to form C(sp³ )-C(sp² ) bonds by visible-light-driven intermolecular reductive ene-yne coupling has been successfully developed. The process relies on the ability of the Hantzsch ester to contribute in both SET and HAT processes through a unified cobalt and iridium catalytic system. This procedure avoids the use of stoichiometric amounts of reducing metallic reagents, which is translated into high functional-group tolerance and atom economy.

SUBMITTER: Gonzalez MJ

PROVIDER: S-EPMC6916364 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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Visible-Light-Driven Intermolecular Reductive Ene-Yne Coupling by Iridium/Cobalt Dual Catalysis for C(sp3 )-C(sp2 ) Bond Formation.

González María J MJ Breit Bernhard B

Chemistry (Weinheim an der Bergstrasse, Germany) 20191108 69

A new methodology to form C(sp3 )-C(sp2 ) bonds by visible-light-driven intermolecular reductive ene-yne coupling has been successfully developed. The process relies on the ability of the Hantzsch ester to contribute in both SET and HAT processes through a unified cobalt and iridium catalytic system. This procedure avoids the use of stoichiometric amounts of reducing metallic reagents, which is translated into high functional-group tolerance and atom economy. ...[more]

PMID: 31549749

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