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FluoroTome 1: An Apparatus for Tomographic Imaging of Radio-Fluorogenic (RFG) Gels.

ABSTRACT: Radio-fluorogenic (RFG) gels become permanently fluorescent when exposed to high-energy radiation with the intensity of the emission proportional to the local dose of radiation absorbed. An apparatus is described, FluoroTome 1, that is capable of taking a series of tomographic images (thin slices) of the fluorescence of such an irradiated RFG gel on-site and within minutes of radiation exposure. These images can then be compiled to construct a 3D movie of the dose distribution within the gel. The historical development via a laboratory-bench prototype to a readily transportable, user-friendly apparatus is described. Instrumental details and performance tests are presented.

SUBMITTER: Warman JM

PROVIDER: S-EPMC6918256 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature

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FluoroTome 1: An Apparatus for Tomographic Imaging of Radio-Fluorogenic (RFG) Gels.

Warman John M JM de Haas Matthijs P MP Luthjens Leonard H LH Yao Tiantian T Navarro-Campos Julia J Yuksel Sölen S Aarts Jan J Thiele Simon S Houter Jacco J In Het Zandt Wilco W

Polymers 20191023 11

Radio-fluorogenic (RFG) gels become permanently fluorescent when exposed to high-energy radiation with the intensity of the emission proportional to the local dose of radiation absorbed. An apparatus is described, FluoroTome 1, that is capable of taking a series of tomographic images (thin slices) of the fluorescence of such an irradiated RFG gel on-site and within minutes of radiation exposure. These images can then be compiled to construct a 3D movie of the dose distribution within the gel. Th ...[more]

PMID: 31652759

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