Ontology highlight
ABSTRACT:
SUBMITTER: Palacios R
PROVIDER: S-EPMC6921433 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Palacios Ricardo R Shah Seema K SK
Trials 20191219 Suppl 2
Human challenge trials (HCTs) deliberately infect participants in order to test vaccines and treatments in a controlled setting, rather than enrolling individuals with natural exposure to a disease. HCTs are therefore potentially powerful tools to prepare for future outbreaks of emerging infectious diseases. Yet when an infectious disease is emerging, there is often substantial risk and uncertainty about its complications, and few available interventions, making an HCT ethically complex. In ligh ...[more]