Ontology highlight
ABSTRACT:
SUBMITTER: Wang T
PROVIDER: S-EPMC6922320 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Wang Tong T Goyal Akshit A Dubinkina Veronika V Maslov Sergei S
PLoS computational biology 20191219 12
The human gut microbiome is a complex ecosystem, in which hundreds of microbial species and metabolites coexist, in part due to an extensive network of cross-feeding interactions. However, both the large-scale trophic organization of this ecosystem, and its effects on the underlying metabolic flow, remain unexplored. Here, using a simplified model, we provide quantitative support for a multi-level trophic organization of the human gut microbiome, where microbes consume and secrete metabolites in ...[more]