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Proteome-Level Functional Redundancy in the Human Gut Microbiome

ABSTRACT: Here, we quantify the proteome-level functional redundancy in the human gut microbiome using metaproteomics and network approaches.In particular, we used an ultra-deep metaproteomics approach based on high-pH reverse phase fractionation. The data analysis revealed high protein-level functional redundancy and high nestedness in proteomic content networks - bipartite graphs that connect taxa with their expressed functions.

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Human Gut Metagenome

TISSUE(S): Gut

SUBMITTER: Leyuan Li

LAB HEAD: Daniel Figeys

PROVIDER: PXD027297 | Pride | 2023-06-08

REPOSITORIES: Pride

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			Action	DRS
	Leyuan_20201015_Exploris_MGMP_fractionation_CTRL_1_01.raw	Raw
	Leyuan_20201015_Exploris_MGMP_fractionation_CTRL_1_02.raw	Raw
	Leyuan_20201015_Exploris_MGMP_fractionation_CTRL_1_03.raw	Raw
	Leyuan_20201015_Exploris_MGMP_fractionation_CTRL_1_04.raw	Raw
	Leyuan_20201015_Exploris_MGMP_fractionation_CTRL_1_05.raw	Raw

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