Ontology highlight
ABSTRACT:
SUBMITTER: Smyth LJ
PROVIDER: S-EPMC6925854 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Smyth L J LJ Kilner J J Maxwell A P AP McKnight A J AJ
BMC research notes 20191221 1
<h4>Objectives</h4>Genomic DNA (gDNA) is the optimal source of DNA for methylation analysis. This study compared methylation patterns in gDNA derived from blood with cell-line derived DNA (clDNA) from the same individuals. The clDNA had been generated via an Epstein-Barr virus transformation of the participant's lymphocytes. This analysis sought to determine whether clDNA has the potential to be utilised in lieu of finite/unavailable gDNA in methylation analyses using Illumina Infinium Methylati ...[more]