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Michael Addition Reaction Catalyzed by Imidazolium Chloride to Protect Amino Groups and Construct Medium Ring Heterocycles.

ABSTRACT: An effective approach for amino protection and construction of a seven-membered ring has been developed. The method uses imidazolium chloride to carry out the Michael addition reaction at low temperatures and perform amino deprotection or construction of a seven-membered ring at high temperatures.

SUBMITTER: Dai Z

PROVIDER: S-EPMC6930643 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature

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Michael Addition Reaction Catalyzed by Imidazolium Chloride to Protect Amino Groups and Construct Medium Ring Heterocycles.

Dai Zeshu Z Tian Qingqiang Q Li Yanwu Y Shang Suqin S Luo Wen W Wang Xuetong X Li Dan D Zhang Ying Y Li Zhiyao Z Yuan Jianyong J

Molecules (Basel, Switzerland) 20191120 23

An effective approach for amino protection and construction of a seven-membered ring has been developed. The method uses imidazolium chloride to carry out the Michael addition reaction at low temperatures and perform amino deprotection or construction of a seven-membered ring at high temperatures. ...[more]

PMID: 31757097

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