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A halogen-bonding-catalyzed Michael addition reaction.

ABSTRACT: Only a few studies on the use of halogen bonding in catalysis have been published so far. Herein, (benz)imidazolium-based halogen bond donors are used as catalysts in a Michael addition reaction. The most potent catalyst, a rigid atropisomer featuring two iodobenzimidazolium moieties, provided a rate acceleration versus a reference compound of ca. 50.

SUBMITTER: Gliese JP

PROVIDER: S-EPMC5708360 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature

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A halogen-bonding-catalyzed Michael addition reaction.

Gliese Jan-Philipp JP Jungbauer Stefan H SH Huber Stefan M SM

Chemical communications (Cambridge, England) 20171101 88

Only a few studies on the use of halogen bonding in catalysis have been published so far. Herein, (benz)imidazolium-based halogen bond donors are used as catalysts in a Michael addition reaction. The most potent catalyst, a rigid atropisomer featuring two iodobenzimidazolium moieties, provided a rate acceleration versus a reference compound of ca. 50. ...[more]

PMID: 29064505

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