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Supporting data for positron emission tomography-based risk modelling using a fixed-instead of a relative thresholding method for total metabolic tumor volume determination.


ABSTRACT: Total metabolic tumor volume (TMTV) was measured in 510 patients with DLBCL participating in the PETAL trial. The present data provide information about the prognostic impact of total metabolic tumor volume using the fixed standardized uptake value (SUV4) instead of the relative SUV41max thresholding method. A Bland-Altman plot was created to compare both methods. For TMTV assessed by the SUV4 method a Cox regression was applied to determine its effect on time to progression, progression-free survival, and overall survival. Kaplan-Meier curves and corresponding hazard ratios were used to estimate the effect of TMTV alone or in combination with interim positron emission tomography response on patients' survival. The data relate to the research article entitled "Dynamic risk assessment based on positron emission tomography scanning in diffuse large B-cell lymphoma: post-hoc analysis from the PETAL trial" [1].

SUBMITTER: Schmitz C 

PROVIDER: S-EPMC6931116 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

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Supporting data for positron emission tomography-based risk modelling using a fixed-instead of a relative thresholding method for total metabolic tumor volume determination.

Schmitz Christine C   Hüttmann Andreas A   Müller Stefan P SP   Hanoun Maher M   Boellaard Ronald R   Brinkmann Marcus M   Jöckel Karl-Heinz KH   Dührsen Ulrich U   Rekowski Jan J  

Data in brief 20191212


Total metabolic tumor volume (TMTV) was measured in 510 patients with DLBCL participating in the PETAL trial. The present data provide information about the prognostic impact of total metabolic tumor volume using the fixed standardized uptake value (SUV<sub>4</sub>) instead of the relative SUV<sub>41max</sub> thresholding method. A Bland-Altman plot was created to compare both methods. For TMTV assessed by the SUV<sub>4</sub> method a Cox regression was applied to determine its effect on time to  ...[more]

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