Ontology highlight
ABSTRACT:
SUBMITTER: Ling X
PROVIDER: S-EPMC6933407 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Ling Xiaozheng X Zhang Guowei G Xia Yuguo Y Zhu Qingwei Q Zhang Juntao J Li Qing Q Niu Xin X Hu Guowen G Yang Yunlong Y Wang Yang Y Deng Zhifeng Z
Journal of cellular and molecular medicine 20191031 1
Endogenous neurogenesis holds promise for brain repair and long-term functional recovery after ischaemic stroke. However, the effects of exosomes from human urine-derived stem cells (USC-Exos) in neurogenesis remain unclear. This study aimed to investigate whether USC-Exos enhanced neurogenesis and promoted functional recovery in brain ischaemia. By using an experimental stroke rat model, we found that intravenous injection of USC-Exos enhanced neurogenesis and alleviated neurological deficits i ...[more]