Ontology highlight
ABSTRACT:
SUBMITTER: Bjorck ML
PROVIDER: S-EPMC6934443 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Björck Markus L ML Vilhjálmsdóttir Jóhanna J Hartley Andrew M AM Meunier Brigitte B Näsvik Öjemyr Linda L Maréchal Amandine A Brzezinski Peter P
Scientific reports 20191227 1
In cytochrome c oxidase (CytcO) reduction of O<sub>2</sub> to water is linked to uptake of eight protons from the negative side of the membrane: four are substrate protons used to form water and four are pumped across the membrane. In bacterial oxidases, the substrate protons are taken up through the K and the D proton pathways, while the pumped protons are transferred through the D pathway. On the basis of studies with CytcO isolated from bovine heart mitochondria, it was suggested that in mito ...[more]