Ontology highlight
ABSTRACT:
SUBMITTER: Lee SY
PROVIDER: S-EPMC6934743 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Lee Suh-Young SY Won Ha-Kyeong HK Kim Byung-Keun BK Kim Sae-Hoon SH Chang Yoon-Seok YS Cho Sang-Heon SH Kelly H William HW Tantisira Kelan G KG Park Heung-Woo HW
Scientific reports 20191227 1
Derangement in bone mineral density (BMD) caused by glucocorticoid is well-known. The present study aimed to find key biological pathways associated with low BMD after glucocorticoid treatment in asthmatics using gene expression profiles of peripheral blood cells. We utilized immortalized B cells (IBCs) from 32 childhood asthmatics after multiple oral glucocorticoid bursts and peripheral blood mononuclear cells (PBMCs) from 17 adult asthmatics after a long-term use of oral glucocorticoid. We sea ...[more]