Ontology highlight
ABSTRACT:
SUBMITTER: Graham BS
PROVIDER: S-EPMC6936610 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Graham Barney S BS Gilman Morgan S A MSA McLellan Jason S JS
Annual review of medicine 20190101
Enabled by new approaches for rapid identification and selection of human monoclonal antibodies, atomic-level structural information for viral surface proteins, and capacity for precision engineering of protein immunogens and self-assembling nanoparticles, a new era of antigen design and display options has evolved. While HIV-1 vaccine development has been a driving force behind these technologies and concepts, clinical proof-of-concept for structure-based vaccine design may first be achieved fo ...[more]