Ontology highlight
ABSTRACT:
SUBMITTER: Lan J
PROVIDER: S-EPMC6940979 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Lan Jingjing J Zhang Ruihua R Li Pengfei P Chen Junhao J Xie Zhijing Z Jiang Shijin S
Animals : an open access journal from MDPI 20191202 12
Duck astrovirus type 1 (DAstV-1) infection constitutes a cause of viral hepatitis in ducklings and little is known about the B-cell epitope of DAstV-1. In this study, a monoclonal antibody (mAb) 3D2 against open reading frame 2 (ORF2) protein of DAstV-1 was used to identify the possible epitope in the four serotypes of DAstV. The mAb 3D2 showed no neutralization activity to DAstV-1, and reacted with the conserved linear B-cell epitopes of <sup>454</sup>STTESA<sup>459</sup> in DAstV-1 ORF2 protei ...[more]