IRF4 translocation status in pediatric follicular and diffuse large B-cell lymphoma patients enrolled in Children's Oncology Group trials.
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ABSTRACT:
SUBMITTER: Chisholm KM
PROVIDER: S-EPMC6941672 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
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IRF4 translocation status in pediatric follicular and diffuse large B-cell lymphoma patients enrolled in Children's Oncology Group trials.
Chisholm Karen M KM Mohlman Jeffrey J Liew Michael M Termuhlen Amanda A Cairo Mitchell S MS Gross Thomas G TG Perkins Sherrie L SL Miles Rodney R RR
Pediatric blood & cancer 20190422 8
Large B-cell lymphoma with IRF4 rearrangement is a provisional entity in the 2017 World Health Organization classification. In order to characterize these lymphomas in children from the United States, IRF4 FISH and immunohistochemical stains were performed on 32 follicular lymphoma and diffuse large B-cell lymphoma (DLBCL) from Children's Oncology Group studies. Two DLBCLs (6%) had IRF4 rearrangements, one involving the ileocecal valve and another involving the tonsil and cerebrospinal fluid. Bo ...[more]
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2009-06-25 | GSE11877 | GEO
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Project description:Gene Expression Classifiers for Minimal Residual Disease and Relapse Free Survival Improve Outcome Prediction and Risk Classification in Children with High Risk Acute Lymphoblastic Leukemia: A Children's Oncology Group Study
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