Unknown

Dataset Information

0

Catalytic processing in ruthenium-based polyoxometalate coacervate protocells.


ABSTRACT: The development of programmable microscale materials with cell-like functions, dynamics and collective behaviour is an important milestone in systems chemistry, soft matter bioengineering and synthetic protobiology. Here, polymer/nucleotide coacervate micro-droplets are reconfigured into membrane-bounded polyoxometalate coacervate vesicles (PCVs) in the presence of a bio-inspired Ru-based polyoxometalate catalyst to produce synzyme protocells (Ru4PCVs) with catalase-like activity. We exploit the synthetic protocells for the implementation of multi-compartmentalized cell-like models capable of collective synzyme-mediated buoyancy, parallel catalytic processing in individual horseradish peroxidase-containing Ru4PCVs, and chemical signalling in distributed or encapsulated multi-catalytic protocell communities. Our results highlight a new type of catalytic micro-compartment with multi-functional activity and provide a step towards the development of protocell reaction networks.

SUBMITTER: Gobbo P 

PROVIDER: S-EPMC6941959 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC6024302 | biostudies-other
| S-EPMC7722712 | biostudies-literature
| S-EPMC6851677 | biostudies-literature
| S-EPMC4756681 | biostudies-literature
| S-EPMC6128941 | biostudies-literature
| S-EPMC8163383 | biostudies-literature
| S-EPMC6618027 | biostudies-literature
| S-EPMC7560875 | biostudies-literature
| S-EPMC8217494 | biostudies-literature
| S-EPMC5885784 | biostudies-literature