Glycolysis metabolic changes in sperm cryopreservation based on a targeted metabolomic strategy.
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ABSTRACT:
SUBMITTER: Fu L
PROVIDER: S-EPMC6947125 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
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Glycolysis metabolic changes in sperm cryopreservation based on a targeted metabolomic strategy.
Fu Longlong L Liu Ying Y An Qi Q Zhang Jianfang J Tong Yue Y Zhou Fang F Lu Wenhong W Liang Xiaowei X Gu Yiqun Y
International journal of clinical and experimental pathology 20190501 5
Our aim was to identify potential metabolomic pathway changes in the sperm cryopreservation process and to find new markers of human sperm freezability. Targeted metabolomic experiments were used to identify the quantitative metabolomic compound characterization of human sperm cryopreservation. A KEGG pathway analysis was used for these deregulated compounds. A total of 16 significantly deregulated compounds was identified between fresh and post-thawed sperm; of these, 7 were downregulated and 9 ...[more]
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