Ontology highlight
ABSTRACT:
SUBMITTER: Yang Y
PROVIDER: S-EPMC6948009 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Yang Yaoyu Y Nemhauser Jennifer L JL Klavins Eric E
ACS synthetic biology 20190501 5
Engineered systems that control cellular differentiation and pattern formation are essential for applications like tissue engineering, biomaterial fabrication, and synthetic ecosystems. Synthetic circuits that can take on multiple states have been made to engineer multicellular systems. However, how to use these states to drive interesting cellular behavior remains challenging. Here, we present a cellular differentiation program involving a novel synthetic bistable switch coupled to an antibioti ...[more]