Ontology highlight
ABSTRACT:
SUBMITTER: Teneggi V
PROVIDER: S-EPMC6951458 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Clinical and translational science 20190909 1
In the last decade, drug development has tackled substantial challenges to improve efficiency and facilitate access to innovative medicines. Integrated clinical protocols and the investigation of targeted oncology drugs in healthy volunteers (HVs) have emerged as modalities with an increase in scope and complexity of early clinical studies and first-in-human (FIH) studies in particular. However, limited work has been done to explore the impact of these two modalities, alone or in combination, on ...[more]