Ontology highlight
ABSTRACT:
SUBMITTER: Zhang H
PROVIDER: S-EPMC6953877 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Zhang Hong H Yarinome Kenji K Kawakami Ryosuke R Otomo Kohei K Nemoto Tomomi T Okamura Yosuke Y
PloS one 20200110 1
In order to achieve deep tissue imaging, a number of optical clearing agents have been developed. However, in a conventional microscopy setup, an objective lens can only be moved until it is in contact with a coverslip, which restricts the maximum focusing depth into a cleared tissue specimen. Until now, it is still a fact that the working distance of a high magnification objective lens with a high numerical aperture is always about 100 μm. In this study, a polymer thin film (also called as nano ...[more]