Ontology highlight
ABSTRACT:
SUBMITTER: Hu J
PROVIDER: S-EPMC6956214 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Hu Jinghui J Wang Li L Zhao Wei W Huang Yujie Y Wang Zhe Z Shen Heping H
Oncology letters 20191211 2
The present study aimed to investigate the involvement of long noncoding RNA mi-R4435-2HG in ovarian carcinoma. mi-R4435-2HG and Rho-associated protein kinase 2 (ROCK2) were demonstrated to both be upregulated in ovarian carcinoma. mi-R4435-2HG and ROCK2 were positively correlated in both tumor and healthy tissues. mi-R4435-2HG overexpression mediated the upregulation of ROCK2, while upregulation of ROCK2 did not affect mi-R4435-2HG. Overexpression of mi-R4435-2HG and ROCK2 led to promoted proli ...[more]